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A granular cell tumor which recurs locally after excision would also tend to indicate a malignant situation. As a result, granular cell breast tumors will tend to stain positive for the S protein, which also supports the idea that they derive from Schwann cells Breast schwannoma and breast neurofibroma also derive mostly from Schwann cells, which are also found in malignant peripheral nerve sheath tumors of the breast. However, bear in mind that for benign granular cell breast tumors, surgical excision is usually a complete cure. Local recurrence is typically rapid, however, usually within 1 year of the original surgery. Unfortunately, removal of granular cell breast tumors tends to be a fairly major surgerybecause they have a tendency to attach themselves to adjacent muscles and other structures.

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Mammograms tend to show a suspicious, spiculated mass, possibly with infiltrative margins.

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Granular Cell Tumor of the breast

Features of breast granular cell tumors suggestive of malignancy   Histological features of granular cell breast tumors which are more suggestive of malignancy include a larger size tumor greater than 5cmcellular and nuclear pleomorphism, increased mitotic activity, prominent nucleoli, and the presence of necrosis. As a result, granular cell breast tumors will tend to stain positive for the S protein, which also supports the idea that they derive from Schwann cells Breast schwannoma and breast neurofibroma also derive mostly from Schwann cells, which are also found in malignant peripheral nerve sheath tumors of the breast. Microscopic and histological aspects of breast granular cell tumors   Histological analysis of granular cell breast tumors typically reveals sheets and nests of polygonal cells. A granular cell tumor, sometimes also called breast granular cell myoblastomais an uncommon neoplastic cell growth than originates in the Schwann cells of the peripheral nervous system. Granular Cell Tumor of the breast   A granular cell tumor, sometimes also called breast granular cell myoblastomais an uncommon neoplastic cell growth than originates in the Schwann cells of the peripheral nervous system. Unfortunately, removal of granular cell breast tumors tends to be a fairly major surgerybecause they have a tendency to attach themselves to adjacent muscles and other structures.

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Comments

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